UBP7/YIL156W Summary Help

Standard Name UBP7 1
Systematic Name YIL156W
Feature Type ORF, Verified
Description Ubiquitin-specific protease that cleaves ubiquitin-protein fusions; UBP7 has a paralog, UBP11, that arose from the whole genome duplication (2, 3)
Name Description UBiquitin-specific Protease 1
Chromosomal Location
ChrIX:48091 to 51306 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All UBP7 GO evidence and references
  View Computational GO annotations for UBP7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
67 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 12
  • Co-purification: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 17

Genetic Interactions
  • Dosage Growth Defect: 4
  • Dosage Lethality: 1
  • Negative Genetic: 10
  • Phenotypic Suppression: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,071
Molecular Weight (Da) 123,133
Isoelectric Point (pI) 7.96
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:48091 to 51306 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3216 48091..51306 1994-12-10 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001418
References cited on this page View Complete Literature Guide for UBP7
1) Amerik AY, et al.  (2000) Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Biol Chem 381(9-10):981-92
2) Hochstrasser M  (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61