UBP5/YER144C Summary Help

UBP5 BASIC INFORMATION

Standard Name UBP5 1
Systematic Name YER144C
Feature Type ORF, Verified
Description Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck (1, 2, 3)
Name Description UBiquitin-specific Protease 1
GO Annotations All UBP5 GO evidence and references
    View Computational GO annotations for UBP5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All UBP5 Phenotype details and references
Classical genetics
overexpression
Large-scale survey
null
overexpression
Interactions UBP5 All interactions details and references
  View additional details at BioGRID
29 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Protein-RNA: 1
  • Two-hybrid: 9

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 12
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Sequence Information
ChrV:460218 to 457801 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2000-03-16 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2418 460218..457801 2000-03-16 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000946

UBP5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for UBP5]

1) Xiao W, et al.  (1994) UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product. Yeast 10(11):1497-502
2) Papa FR, et al.  (1999) Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome. Mol Biol Cell 10(3):741-56
3) Amerik A, et al.  (2006) A conserved late endosome-targeting signal required for Doa4 deubiquitylating enzyme function. J Cell Biol 175(5):825-35