UBI4/YLL039C Summary Help

UBI4 BASIC INFORMATION

Standard Name UBI4 1
Systematic Name YLL039C
Alias SCD2 , UB14
Feature Type ORF, Verified
Description Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats (1, 2, 3, 4, 5, 6)
Name Description Ubiquitin 1
GO Annotations All UBI4 GO evidence and references
    View Computational GO annotations for UBI4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All UBI4 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions UBI4 All interactions details and references
1273 total interaction(s) for 1169 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1096
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 49
  • Biochemical Activity: 8
  • Co-crystal Structure: 6
  • Far Western: 1
  • Protein-peptide: 2
  • Reconstituted Complex: 22
  • Two-hybrid: 14
Genetic Interactions
  • Dosage Rescue: 17
  • Phenotypic Enhancement: 39
  • Phenotypic Suppression: 6
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 7
  • Synthetic Rescue: 3
Sequence Information
ChrXII:65206 to 64061 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1146 65206..64061 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS
Primary SGDIDS000003962

UBI4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for UBI4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for UBI4]

1) Ozkaynak E, et al.  (1987) The yeast ubiquitin genes: a family of natural gene fusions. EMBO J 6(5):1429-39
2) Shih SC, et al.  (2000) Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J 19(2):187-98
3) Finley D, et al.  (1994) Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant. Mol Cell Biol 14(8):5501-9
4) Lucero P, et al.  (2000) Monoubiquitination is sufficient to signal internalization of the maltose transporter in Saccharomyces cerevisiae. J Bacteriol 182(1):241-3
5) Finley D, et al.  (1987) The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses. Cell 48(6):1035-46
6) Ozkaynak E, et al.  (1984) The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein. Nature 312(5995):663-6