UBA3/YPR066W Summary Help

Standard Name UBA3 1
Systematic Name YPR066W
Feature Type ORF, Verified
Description Protein that activates Rub1p (NEDD8) before neddylation; acts together with Ula1p; may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern (1, 2)
Name Description UBiquitin-like protein-Activating enzyme 1
Chromosomal Location
ChrXVI:681213 to 682112 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All UBA3 GO evidence and references
  View Computational GO annotations for UBA3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Classical genetics
null
Large-scale survey
null
overexpression
Resources
133 total interaction(s) for 99 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 79
  • Positive Genetic: 35
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 299
Molecular Weight (Da) 33,278
Isoelectric Point (pI) 4.57
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:681213 to 682112 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..900 681213..682112 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006270
References cited on this page View Complete Literature Guide for UBA3
1) Liakopoulos D, et al.  (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91