UBA1/YKL210W Summary

UBA1 BASIC INFORMATION

Standard Name	UBA1
Systematic Name	YKL210W
Feature Type	ORF, Verified
Description	Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability (1)
Name Description	UBiquitin Activating 1

GO Annotations	All UBA1 GO evidence and references
	View Computational GO annotations for UBA1
Molecular Function
Manually curated	ubiquitin activating enzyme activity (IDA)
Biological Process
Manually curated	protein ubiquitination (IDA)
Cellular Component
Manually curated	cytoplasm (IDA) nucleus (IDA)

Mutant Phenotype	All UBA1 Phenotype details and references
Classical genetics
conditional	Fzo1p accumulation: increased
Large-scale survey
null	inviable
repressible	mitochondrial morphology: abnormal

Interactions	UBA1 All interactions details and references
	45 total interaction(s) for 43 unique genes/features.
Physical Interactions	Affinity Capture-MS: 31 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 4 Co-crystal Structure: 1 Co-purification: 1 Reconstituted Complex: 1
Genetic Interactions	Phenotypic Suppression: 1 Synthetic Rescue: 4

Sequence Information

ChrXI:39164 to 42238 | |

Genetic position: -153.3 cM

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3075	39164..42238	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001693

UBA1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for UBA1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for UBA1]

1)	McGrath JP, et al. (1991) UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme. EMBO J 10(1):227-36

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