TSR3/YOR006C Summary Help

Standard Name TSR3 1
Systematic Name YOR006C
Feature Type ORF, Verified
Description Protein required for 20S pre-rRNA processing; involved in processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; relative distribution to the nucleus increases upon DNA replication stress (1, 2, 3)
Name Description Twenty S rRNA accumulation 1
Chromosomal Location
ChrXV:338621 to 337680 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TSR3 GO evidence and references
  View Computational GO annotations for TSR3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
repressible
Resources
50 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 4
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 25
  • Positive Genetic: 20

Resources
Expression Summary
histogram
Resources
Length (a.a.) 313
Molecular Weight (Da) 35,686
Isoelectric Point (pI) 5.62
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:338621 to 337680 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..942 338621..337680 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005532
References cited on this page View Complete Literature Guide for TSR3
1) Li Z, et al.  (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76