Standard Name	TRS23 1
Systematic Name	YDR246W
Feature Type	ORF, Verified
Description	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic; human homolog is TRAPPC4 (1, 2, 3)
Name Description	TRapp Subunit 1

Chromosomal Location	ChrIV:954288 to 954947 | ORF Map | GBrowse

	View Computational GO annotations for TRS23
Molecular Function
Manually curated	contributes_to Rab guanyl-nucleotide exchange factor activity (IDA, IMP)
Biological Process
Manually curated	chromosome organization (IMP) ER to Golgi vesicle-mediated transport (IGI, IMP)
Cellular Component
Manually curated	TRAPP complex (IDA)

Classical genetics
conditional	chromosome/plasmid maintenance: abnormal colony sectoring: increased
reduction of function	cold sensitivity: increased heat sensitivity: increased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable resistance to clioquinol: decreased
reduction of function	competitive fitness: increased telomere length: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	51 total interaction(s) for 15 unique genes/features.
Physical Interactions	Affinity Capture-MS: 18 Affinity Capture-RNA: 2 Affinity Capture-Western: 10 Co-fractionation: 5 Co-purification: 1 Two-hybrid: 7
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 2 Synthetic Growth Defect: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:954288 to 954947 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..660 954288..954947 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002654