Standard Name	TRS120 1
Systematic Name	YDR407C
Feature Type	ORF, Verified
Description	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic (1, 2)
Name Description	TRapp Subunit 1

Chromosomal Location	ChrIV:1287938 to 1284069 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for TRS120
Molecular Function
Manually curated	contributes_to Rab guanyl-nucleotide exchange factor activity (IMP)
Biological Process
Manually curated	early endosome to Golgi transport (IMP) intra-Golgi vesicle-mediated transport (IMP) regulation of Rab GTPase activity (IMP)
Cellular Component
Manually curated	early endosome (IDA) trans-Golgi network (IDA) TRAPP complex (IDA)

Classical genetics
conditional	endomembrane system morphology: abnormal invertase secretion: absent invertase secretion: decreased GFP-Snc1p distribution: abnormal Sec21p-GFP distribution: abnormal Chs3p-GFP distribution: abnormal
Large-scale survey
null	haploinsufficient inviable resistance to ciclopirox olamine: decreased
reduction of function	competitive fitness: decreased resistance to hydroxyurea: decreased
repressible	cell cycle progression in S phase: abnormal mitochondrial morphology: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	56 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 24 Affinity Capture-RNA: 1 Affinity Capture-Western: 18 Reconstituted Complex: 2 Two-hybrid: 3
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 4 Phenotypic Enhancement: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1287938 to 1284069 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..3870 1287938..1284069 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002815