TRM13/YOL125W Summary Help

Standard Name TRM13 1
Systematic Name YOL125W
Feature Type ORF, Verified
Description 2'-O-methyltransferase; responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases (1, 2)
Name Description TRna Methyltransferase 1
Chromosomal Location
ChrXV:83834 to 85264 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TRM13 GO evidence and references
  View Computational GO annotations for TRM13
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Large-scale survey
null
overexpression
Resources
13 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Biochemical Activity: 10
  • PCA: 1

Genetic Interactions
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 476
Molecular Weight (Da) 54,095
Isoelectric Point (pI) 8.22
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:83834 to 85264 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1431 83834..85264 2006-01-05 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005485
References cited on this page View Complete Literature Guide for TRM13
1) Wilkinson ML, et al.  (2007) The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4. RNA 13(3):404-13
2) Tkaczuk KL  (2010) Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site. J Mol Model 16(3):599-606