TPC1/YGR096W Summary Help

Standard Name TPC1
Systematic Name YGR096W
Feature Type ORF, Verified
Description Mitochondrial membrane transporter; mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family (1)
Name Description Thiamine Pyrophosphate Carrier
Chromosomal Location
ChrVII:676621 to 677565 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TPC1 GO evidence and references
  View Computational GO annotations for TPC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
15 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • PCA: 1
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Lethality: 2
  • Negative Genetic: 9
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 314
Molecular Weight (Da) 35,137
Isoelectric Point (pI) 10.79
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:676621 to 677565 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..945 676621..677565 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003328
References cited on this page View Complete Literature Guide for TPC1
1) Marobbio CM, et al.  (2002) Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate. EMBO J 21(21):5653-61