TOM71/YHR117W Summary Help

Standard Name TOM71 1
Systematic Name YHR117W
Alias TOM72
Feature Type ORF, Verified
Description Mitochondrial outer membrane protein; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; TOM71 has a paralog, TOM70, that arose from the whole genome duplication (1, 2, 3)
Name Description Translocase of the Outer Mitochondrial membrane 1
Chromosomal Location
ChrVIII:342349 to 344268 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TOM71 GO evidence and references
  View Computational GO annotations for TOM71
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
44 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 8
  • Co-crystal Structure: 3
  • Co-fractionation: 1
  • PCA: 1
  • Reconstituted Complex: 2

Genetic Interactions
  • Negative Genetic: 10
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 639
Molecular Weight (Da) 71,856
Isoelectric Point (pI) 6.03
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:342349 to 344268 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1920 342349..344268 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001159
References cited on this page View Complete Literature Guide for TOM71
1) Schlossmann J, et al.  (1996) Tom71, a novel homologue of the mitochondrial preprotein receptor Tom70. J Biol Chem 271(30):17890-5
2) Koh JY, et al.  (2001) Overproduction of PDR3 suppresses mitochondrial import defects associated with a TOM70 null mutation by increasing the expression of TOM72 in Saccharomyces cerevisiae. Mol Cell Biol 21(22):7576-86
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61