TNA1/YGR260W Summary Help

Standard Name TNA1 1
Systematic Name YGR260W
Feature Type ORF, Verified
Description High affinity nicotinic acid plasma membrane permease; responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA) (1, 2)
Name Description Transporter of Nicotinic Acid 1
Chromosomal Location
ChrVII:1012485 to 1014089 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TNA1 GO evidence and references
  View Computational GO annotations for TNA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
97 total interaction(s) for 86 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 2
  • PCA: 38

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 41
  • Positive Genetic: 5
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 534
Molecular Weight (Da) 60,134
Isoelectric Point (pI) 6.8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:1012485 to 1014089 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1605 1012485..1014089 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003492
References cited on this page View Complete Literature Guide for TNA1
1) Llorente B and Dujon B  (2000) Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w). FEBS Lett 475(3):237-41
2) Klebl F, et al.  (2000) Transcription of the yeast TNA1 gene is not only regulated by nicotinate but also by p-aminobenzoate. FEBS Lett 481(1):86-7