TMN2/YDR107C Summary Help

Standard Name TMN2 1
Systematic Name YDR107C
Feature Type ORF, Verified
Description Protein with a role in cellular adhesion and filamentous growth; similar to Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments; TMN2 has a paralog, EMP70, that arose from the whole genome duplication (1, 2, 3)
Name Description TransMembrane Nine 1
Chromosomal Location
ChrIV:671034 to 669016 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TMN2 GO evidence and references
  View Computational GO annotations for TMN2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
unspecified
Resources
18 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • PCA: 2
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 5
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 672
Molecular Weight (Da) 76,346
Isoelectric Point (pI) 7.46
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:671034 to 669016 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2019 671034..669016 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002514
References cited on this page View Complete Literature Guide for TMN2
1) Froquet R, et al.  (2008) Control of Cellular Physiology by TM9 Proteins in Yeast and Dictyostelium. J Biol Chem 283(11):6764-6772
2) Schimmoller F, et al.  (1998) Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. Gene 216(2):311-8
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61