Standard Name	TMA19 1
Systematic Name	YKL056C
Alias	MMI1 2
Feature Type	ORF, Verified
Description	Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress (1, 2, 3, 4, 5)
Name Description	Translation Machinery Associated 1

Chromosomal Location	ChrXI:334915 to 334412 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for TMA19
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	cellular response to oxidative stress (IMP) cytoplasmic translation (IMP)
Cellular Component
Manually curated	cytosol (IDA) mitochondrion (IDA) colocalizes_with ribosome (IDA)
High-throughput	cytoplasm (IDA)

Retired Name	RBF18

Classical genetics
null	oxidative stress resistance: increased replicative lifespan: increased resistance to benomyl: decreased resistance to menadione: decreased resistance to methyl methanesulfonate: increased
overexpression	resistance to arsenite ion: increased
Large-scale survey
null	auxotrophy cell cycle progression in G1 phase: delayed competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased replicative lifespan: increased resistance to sodium selenide: decreased resistance to quinine: decreased resistance to nickel sulfate: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	92 total interaction(s) for 75 unique genes/features.
Physical Interactions	Affinity Capture-MS: 22 Affinity Capture-RNA: 8 Biochemical Activity: 1 PCA: 3
Genetic Interactions	Negative Genetic: 35 Phenotypic Suppression: 1 Positive Genetic: 15 Synthetic Growth Defect: 4 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:334915 to 334412 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..504 334915..334412 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001539