TMA17/YDL110C Summary Help

Standard Name TMA17 1
Systematic Name YDL110C
Feature Type ORF, Verified
Description Protein of unknown function that associates with ribosomes; heterozygous deletion demonstrated increases in chromosome instability in a rad9 deletion background; protein abundance is decreased upon intracellular iron depletion (1, 2, 3)
Name Description Translation Machinery Associated 1
Chromosomal Location
ChrIV:264964 to 264512 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TMA17 GO evidence and references
  View Computational GO annotations for TMA17
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Large-scale survey
null
Resources
66 total interaction(s) for 59 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • PCA: 2
  • Protein-RNA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 10

Genetic Interactions
  • Negative Genetic: 45
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 150
Molecular Weight (Da) 16,771
Isoelectric Point (pI) 4.42
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:264964 to 264512 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..453 264964..264512 2004-02-11 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002268
References cited on this page View Complete Literature Guide for TMA17
1) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307
2) Strome ED, et al.  (2008) Heterozygous Screen in Saccharomyces cerevisiae Identifies Dosage-Sensitive Genes That Affect Chromosome Stability. Genetics 178(3):1193-207
3) Seo HY, et al.  (2008) Proteomic Analysis of Recombinant Saccharomyces cerevisiae Upon Iron Deficiency Induced via Human H-Ferritin Production. J Microbiol Biotechnol 18(8):1368-76