TFB6/YOR352W Summary Help

Standard Name TFB6 1
Systematic Name YOR352W
Feature Type ORF, Verified
Description Subunit of TFIIH complex; facilities dissociation of the Ssl2p helices from TFIIH; expression levels regulated by Arg5,6p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus (1, 2, 3)
Chromosomal Location
ChrXV:997213 to 998244 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TFB6 GO evidence and references
  View Computational GO annotations for TFB6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
12 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-Western: 1
  • Co-purification: 4

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 343
Molecular Weight (Da) 39,274
Isoelectric Point (pI) 4.72
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:997213 to 998244 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1032 997213..998244 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005879
References cited on this page View Complete Literature Guide for TFB6
1) Murakami K, et al.  (2012) Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation. Proc Natl Acad Sci U S A 109(13):4816-21
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Hall DA, et al.  (2004) Regulation of gene expression by a metabolic enzyme. Science 306(5695):482-4