TEM1/YML064C Summary Help

TEM1 BASIC INFORMATION

Standard Name TEM1
Systematic Name YML064C
Feature Type ORF, Verified
Description GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis (1, 2, 3)
Name Description TErmination of M phase 1
GO Annotations All TEM1 GO evidence and references
    View Computational GO annotations for TEM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Regulatory modules predicted: cellcycle ( 221 )
Mutant Phenotype All TEM1 Phenotype details and references
Large-scale survey
null
Interactions TEM1 All interactions details and references
178 total interaction(s) for 108 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 43
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 27
  • Biochemical Activity: 5
  • Co-localization: 3
  • Protein-RNA: 1
  • Reconstituted Complex: 5
  • Two-hybrid: 45
Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 26
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 8
  • Synthetic Rescue: 9
Sequence Information
ChrXIII:145876 to 145139 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..738 145876..145139 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004529

TEM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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Expression Summary histogram

ADDITIONAL INFORMATION for TEM1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SPG1Nomenclature conflictTEM1/YML064C encodes a GTPase involved in the exit from mitosis; it is the homolog of the pombe spg1 gene. Do not confuse TEM1/YML064C with the cerevisiae SPG1/YGR236C.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TEM1]

1) Shirayama M, et al.  (1994) The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase. Mol Cell Biol 14(11):7476-82
2) Shou W, et al.  (1999) Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97(2):233-44
3) Lippincott J, et al.  (2001) The Tem1 small GTPase controls actomyosin and septin dynamics during cytokinesis. J Cell Sci 114(Pt 7):1379-86