TEL2/YGR099W Summary Help

TEL2 BASIC INFORMATION

Standard Name TEL2 1
Systematic Name YGR099W
Feature Type ORF, Verified
Description Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect (1, 2, 3)
Name Description TELomere maintenance
GO Annotations All TEL2 GO evidence and references
    View Computational GO annotations for TEL2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All TEL2 Phenotype details and references
Classical genetics
conditional
null
Large-scale survey
null
reduction of function
Interactions TEL2 All interactions details and references
  View additional details at BioGRID
67 total interaction(s) for 63 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 4
  • PCA: 1
  • Two-hybrid: 8
Genetic Interactions
  • Negative Genetic: 50
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1
Sequence Information
ChrVII:687903 to 689969 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2067 687903..689969 2004-07-20 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003331

TEL2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for TEL2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TEL2]

1) Runge KW and Zakian VA  (1996) TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 16(6):3094-105
2) Kota RS and Runge KW  (1998) The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA. Nucleic Acids Res 26(6):1528-35
3) Kota RS and Runge KW  (1999) Tel2p, a regulator of yeast telomeric length in vivo, binds to single-stranded telomeric DNA in vitro. Chromosoma 108(5):278-90