SUMMARY PARAGRAPH for TEL13L-YP
TEL13L-Yp, the short Y' (Y'-S) element on the left arm of chromosome XIII, contains an ARS consensus sequence, a region of 36-bp repeats, one uncharacterized ORF YML133C, and two dubious ORFs (YML133W-A, YML133W-B).
The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies (2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).
Other features of TEL13L, the left telomeric region of chromosome XIII, include an X element core sequence TEL13L-XC, a region of X element combinatorial repeats TEL13L-XR, and two stretches of telomeric repeats (TEL13L-TR1, TEL13L-TR2).
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-18