SUMMARY PARAGRAPH for TEL07R-YP
TEL07R-Yp, the long Y' (Y'-L) element on the right arm of chromosome VII, contains an ARS consensus sequence, a region of 36-bp repeats, one verified ORF YRF1-3/YGR296W, and two dubious ORFs (YGR296C-A, YGR296C-B).
The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies(2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).
Other features of TEL07R, the right telomeric region of chromosome VII, include an X element core sequence TEL07R-XC, and a region of X element combinatorial repeats TEL07R-XR.
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Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-18