SUMMARY PARAGRAPH for TEL04R-XC
TEL04R-XC, the X element core sequence on the right arm of chromosome IV, spans 464 bp and contains an ARS consensus sequence, an Abf1p binding site consensus sequence, and a dubious ORF YDR543C.
Small conserved elements of ~475 bp, X element core sequences contain ARS consensus sequences and in most cases Abf1p binding sites, and are the only regions shared by all chromosome ends (2, 1). Between the ARS consensus sequence and the Abf1p binding site is a GC-rich region nearly identical to the meiosis-specific regulatory sequence URS1 (1). Possible functions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (1).
Other features of TEL04R, the right telomeric region of chromosome IV, include X element combinatorial repeats TEL04R-XR, a short stretch of telomeric repeats TEL04R-TR, and a long Y' (Y'-L) element TEL04R-YP.
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-03