TEF1/YPR080W Summary

TEF1 BASIC INFORMATION

Standard Name	TEF1
Systematic Name	YPR080W
Feature Type	ORF, Verified
Description	Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes; may also have a role in tRNA re-export from the nucleus (1, 2) Also known as: EF-1 alpha
Name Description	Translation Elongation Factor 1

GO Annotations	All TEF1 GO evidence and references
	View Computational GO annotations for TEF1
Molecular Function
Manually curated	GDP binding (IDA) GTP binding (IDA) translation elongation factor activity (IMP)
Biological Process
Manually curated	translational elongation (IMP) tRNA export from nucleus (IGI)
Cellular Component
Manually curated	cytoplasm (IDA) eukaryotic translation elongation factor 1 complex (ISS) mitochondrion (IPI) ribosome (TAS)

Interactions	TEF1 All interactions details and references
	105 total interaction(s) for 93 unique genes/features.
Physical Interactions	Affinity Capture-MS: 76 Affinity Capture-RNA: 1 Affinity Capture-Western: 6 Co-crystal Structure: 2 Co-purification: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 10 Phenotypic Suppression: 3 Synthetic Lethality: 1

Sequence Information

ChrXVI:700592 to 701968 | |

Genetic position: 46 cM

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1377	700592..701968	2004-07-21	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006284

TEF1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for TEF1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TEF1]

1)	Schirmaier F and Philippsen P (1984) Identification of two genes coding for the translation elongation factor EF-1 alpha of S. cerevisiae. EMBO J 3(13):3311-5
2)	Murthi A, et al. (2009) Regulation of tRNA Bidirectional Nuclear-Cytoplasmic Trafficking in S. cerevisiae. Mol Biol Cell ()

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