Standard Name	TDA8 1
Systematic Name	YAL064C-A
Alias	YAL065C-A 2
Feature Type	ORF, Uncharacterized
Description	Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene (1, 3)
Name Description	Topoisomerase I Damage Affected 1

Chromosomal Location	ChrI:13743 to 13363 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cellular_component unknown (ND)

Large-scale survey
null	competitive fitness: increased haploinsufficient resistance to benzo[a]pyrene: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	7 total interaction(s) for 7 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2
Genetic Interactions	Negative Genetic: 3 Synthetic Growth Defect: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:13743 to 13363 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..381 13743..13363 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain FL100 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain VL3 S.c. Strain W303 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002140