| Standard Name | TDA10 1 |
|---|---|
| Systematic Name | YGR205W |
| Feature Type | ORF, Verified |
| Description | ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele (1, 2) |
| Name Description | Topoisomerase I Damage Affected 1 |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All TDA10 GO evidence and references
| View Computational GO annotations for TDA10 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated |
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| Cellular Component | |
| High-throughput |
Mutant phenotypes All TDA10 Phenotype evidence and references
| Large-scale survey | |
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| null |
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| Resources |
interactions All TDA10 Interaction evidence and references
| 11 total interaction(s) for 10 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All TDA10 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000003437 |
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References cited on this page View Complete Literature Guide for TDA10
| 1) | Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 |
| 2) | de La Sierra-Gallay IL, et al. (2004) Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase. Proteins 54(4):776-83 |




