TCA17/YEL048C Summary Help

Standard Name TCA17 1
Systematic Name YEL048C
Feature Type ORF, Verified
Description Component of transport protein particle (TRAPP) complex II; TRAPPII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating intra-Golgi and endosome-Golgi traffic; promotes association of TRAPPII-specific subunits with the TRAPP core complex; sedlin related; human Sedlin mutations cause SEDT, a skeletal disorder (1, 2, 3)
Name Description TRAPP Complex Associated protein 1
Chromosomal Location
ChrV:65167 to 64709 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TCA17 GO evidence and references
  View Computational GO annotations for TCA17
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
60 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Affinity Capture-Western: 11
  • Biochemical Activity: 1
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 4
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 152
Molecular Weight (Da) 17,354
Isoelectric Point (pI) 4.47
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:65167 to 64709 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..459 65167..64709 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000774
References cited on this page View Complete Literature Guide for TCA17
1) Montpetit B and Conibear E  (2009) Identification of the Novel TRAPP Associated Protein Tca17. Traffic 10(6):713-23
2) Scrivens PJ, et al.  (2009) TRAPPC2L is a Novel, Highly Conserved TRAPP-Interacting Protein. Traffic 10(6):724-36
3) Choi C, et al.  (2011) Organization and assembly of the TRAPPII complex. Traffic 12(6):715-25