TAH11/YJR046W Summary

TAH11 BASIC INFORMATION

Standard Name	TAH11 1
Systematic Name	YJR046W
Alias	SID2 2 , CDT1 3
Feature Type	ORF, Verified
Description	DNA replication licensing factor, required for pre-replication complex assembly (1, 3)
Name Description	Topo-A Hypersensitive 1

GO Annotations	All TAH11 GO evidence and references
Molecular Function
Manually curated	NOT ATP binding (IDA) NOT DNA replication origin binding (IDA) DNA replication origin binding (IDA)
Biological Process
Manually curated	pre-replicative complex assembly (IDA) regulation of DNA replication initiation (IDA)
Cellular Component
Manually curated	cytoplasm (IDA) nucleus (IDA) pre-replicative complex (IDA, IMP)

Mutant Phenotype	All TAH11 Phenotype details and references
Classical genetics
null	inviable sporulation efficiency: normal vegetative growth: normal
Large-scale survey
null	inviable

Interactions	TAH11 All interactions details and references
	26 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 5 Co-purification: 1 Reconstituted Complex: 8 Two-hybrid: 6
Genetic Interactions	Synthetic Lethality: 4 Synthetic Rescue: 1

Sequence Information

ChrX:522040 to 523854 | |

Last Update

Coordinates: 2009-02-18 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1815	522040..523854	2009-02-18	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003807

TAH11 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for TAH11

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TAH11]

1)	Devault A, et al. (2002) Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae. Curr Biol 12(8):689-94
2)	Jacobson MD, et al. (2001) Mutations in SID2, a novel gene in Saccharomyces cerevisiae, cause synthetic lethality with sic1 deletion and may cause a defect during S phase. Genetics 159(1):17-33
3)	Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207

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