TAH11/YJR046W Summary Help

Standard Name TAH11 1
Systematic Name YJR046W
Alias SID2 2 , CDT1 3
Feature Type ORF, Verified
Description DNA replication licensing factor; required for pre-replication complex assembly (1, 3)
Name Description Topo-A Hypersensitive 1
Chromosomal Location
ChrX:522048 to 523862 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TAH11 GO evidence and references
  View Computational GO annotations for TAH11
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 13 genes
Resources
Classical genetics
null
Large-scale survey
conditional
null
reduction of function
Resources
72 total interaction(s) for 28 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 24
  • Co-purification: 1
  • Reconstituted Complex: 19
  • Two-hybrid: 17

Genetic Interactions
  • Synthetic Lethality: 7
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 604
Molecular Weight (Da) 68,405
Isoelectric Point (pI) 8.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:522048 to 523862 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1815 522048..523862 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003807
References cited on this page View Complete Literature Guide for TAH11
1) Devault A, et al.  (2002) Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae. Curr Biol 12(8):689-94
2) Jacobson MD, et al.  (2001) Mutations in SID2, a novel gene in Saccharomyces cerevisiae, cause synthetic lethality with sic1 deletion and may cause a defect during S phase. Genetics 159(1):17-33
3) Tanaka S and Diffley JF  (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207