TAE1/YBR261C Summary Help

Standard Name TAE1 1
Systematic Name YBR261C
Alias NTM1 2
Feature Type ORF, Verified
Description AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 and Rps25 at N-terminal proline residues; has a role in protein synthesis; fusion protein localizes to the cytoplasm (1, 2, 3)
Name Description Translation Associated Element 1
Chromosomal Location
ChrII:735530 to 734832 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TAE1 GO evidence and references
  View Computational GO annotations for TAE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 56 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
80 total interaction(s) for 79 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 4
  • Two-hybrid: 41

Genetic Interactions
  • Negative Genetic: 2
  • Synthetic Growth Defect: 27

Resources
Expression Summary
histogram
Resources
Length (a.a.) 232
Molecular Weight (Da) 26,068
Isoelectric Point (pI) 4.96
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:735530 to 734832 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..699 735530..734832 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000465
References cited on this page View Complete Literature Guide for TAE1
1) Alamgir M, et al.  (2008) Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. BMC Genomics 9:583
2) Webb KJ, et al.  (2010) Identification of protein N-terminal methyltransferases in yeast and humans. Biochemistry 49(25):5225-35
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91