Standard Name	SWM1 1
Systematic Name	YDR260C
Alias	APC13 2
Feature Type	ORF, Verified
Description	Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation (1, 2, 3, 4)
Name Description	Spore Wall Maturation 1

Chromosomal Location	ChrIV:977229 to 976717 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SWM1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (IPI) ascospore wall assembly (IMP) protein ubiquitination (IPI) regulation of mitotic metaphase/anaphase transition (IMP)
Cellular Component
Manually curated	anaphase-promoting complex (IDA) nucleus (IDA)

Classical genetics
null	cell cycle passage through the metaphase-anaphase transition: delayed resistance to bortezomib: decreased spore wall formation: absent sporulation: absent vegetative growth: decreased rate
Large-scale survey
null	auxotrophy polyphosphate accumulation: abnormal competitive fitness: decreased haploinsufficient heat sensitivity: increased resistance to methanol: decreased resistance to nickel sulfate: decreased resistance to ethanol: decreased resistance to methyl methanesulfonate: decreased resistance to dimethyl sulfoxide: decreased sporulation: normal sporulation: decreased sporulation efficiency: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	195 total interaction(s) for 95 unique genes/features.
Physical Interactions	Affinity Capture-MS: 68 Affinity Capture-RNA: 1 Affinity Capture-Western: 6 Biochemical Activity: 3 Co-fractionation: 1 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 4 Negative Genetic: 67 Phenotypic Suppression: 1 Positive Genetic: 3 Synthetic Growth Defect: 26 Synthetic Lethality: 11 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:977229 to 976717 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..513 977229..976717 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002668