SWC7/YLR385C Summary Help

Standard Name SWC7 1, 2
Systematic Name YLR385C
Alias AWS1
Feature Type ORF, Verified
Description Protein of unknown function; component of the Swr1p complex that incorporates Htz1p into chromatin (1, 2, 3)
Name Description SWr Complex 1, 2
Chromosomal Location
ChrXII:893390 to 892992 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SWC7 GO evidence and references
  View Computational GO annotations for SWC7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Large-scale survey
null
Resources
57 total interaction(s) for 41 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 30
  • Affinity Capture-Western: 2
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 13
  • Positive Genetic: 6
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 132
Molecular Weight (Da) 15,120
Isoelectric Point (pI) 6.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:893390 to 892992 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..399 893390..892992 2004-02-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004377
References cited on this page View Complete Literature Guide for SWC7
1) Krogan NJ, et al.  (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76
2) Kobor MS, et al.  (2004) A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biol 2(5):E131
3) Mizuguchi G, et al.  (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8