Standard Name	SWC4 1
Systematic Name	YGR002C
Alias	EAF2 2 , GOD1
Feature Type	ORF, Verified
Description	Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex (2, 3, 4, 5, 6)
Name Description	SWr Complex

Chromosomal Location	ChrVII:499906 to 498476 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SWC4
Molecular Function
High-throughput	DNA binding (ISS)
Biological Process
Manually curated	chromatin modification (IPI) chromatin remodeling (IDA, IPI) chromosome organization (IMP) DNA repair (IDA) establishment of mitotic sister chromatid cohesion (IMP) histone exchange (IPI)
High-throughput	histone acetylation (IPI)
Cellular Component
Manually curated	histone acetyltransferase complex (IPI) NuA4 histone acetyltransferase complex (IPI) Swr1 complex (IDA)
High-throughput	nucleus (IDA)

Classical genetics
conditional	chromosome/plasmid maintenance: abnormal colony sectoring: increased
null	inviable
reduction of function	resistance to methyl methanesulfonate: decreased
repressible	cell cycle progression through the G2/M phase transition: arrested
Large-scale survey
conditional	chromosome/plasmid maintenance: abnormal heat sensitivity: increased
null	inviable
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	342 total interaction(s) for 209 unique genes/features.
Physical Interactions	Affinity Capture-MS: 93 Affinity Capture-RNA: 1 Affinity Capture-Western: 23 Co-crystal Structure: 2 Co-purification: 1 Two-hybrid: 2
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 3 Synthetic Growth Defect: 107 Synthetic Lethality: 106 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:499906 to 498476 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1431 499906..498476 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003234