Standard Name	SVP26 1
Systematic Name	YHR181W
Alias	ERV26 2
Feature Type	ORF, Verified
Description	Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment (1, 2, 3)
Name Description	Sed5 Vesicle Protein 1

Chromosomal Location	ChrVIII:467228 to 467914 | ORF Map | GBrowse

	View Computational GO annotations for SVP26
Molecular Function
Manually curated	COPII adaptor activity (IMP, IPI)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IDA, IMP) fungal-type cell wall organization (IGI, IMP) protein glycosylation (IMP) protein retention in Golgi apparatus (IMP)
Cellular Component
Manually curated	ER to Golgi transport vesicle (IDA) integral to endoplasmic reticulum membrane (IDA) integral to Golgi membrane (IDA)
High-throughput	endoplasmic reticulum (IDA) integral to membrane (ISM)

Classical genetics
null	Kre2p-GFP accumulation: abnormal Pho8p accumulation: increased N-glycosylated protein modification: decreased resistance to Congo Red: decreased resistance to Calcofluor White: decreased viable
Large-scale survey
null	competitive fitness: increased protein transport: abnormal Pho8p (ALP) modification: decreased resistance to propolis extract: decreased stress resistance: decreased viable
overexpression	cell cycle progression: abnormal vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	74 total interaction(s) for 53 unique genes/features.
Physical Interactions	Affinity Capture-Western: 8 Co-localization: 2 Co-purification: 1 Protein-RNA: 1 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 34 Phenotypic Enhancement: 16 Positive Genetic: 1 Synthetic Growth Defect: 8 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:467228 to 467914 | ORF Map | GBrowse
Last Update	Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..687 467228..467914 2005-11-07 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001224