SVP26/YHR181W Summary Help

Standard Name SVP26 1
Systematic Name YHR181W
Alias ERV26 2
Feature Type ORF, Verified
Description Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment (1, 2, 3)
Name Description Sed5 Vesicle Protein 1
Chromosomal Location
ChrVIII:467228 to 467914 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SVP26 GO evidence and references
  View Computational GO annotations for SVP26
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
81 total interaction(s) for 59 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 13
  • Co-localization: 2
  • Co-purification: 1
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 34
  • Phenotypic Enhancement: 16
  • Positive Genetic: 1
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 228
Molecular Weight (Da) 26,283
Isoelectric Point (pI) 8.51
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:467228 to 467914 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..687 467228..467914 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001224
References cited on this page View Complete Literature Guide for SVP26
1) Inadome H, et al.  (2005) Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments. Mol Cell Biol 25(17):7696-710
2) Bue CA, et al.  (2006) Erv26p Directs Pro-Alkaline Phosphatase into Endoplasmic Reticulum-derived Coat Protein Complex II Transport Vesicles. Mol Biol Cell 17(11):4780-9
3) Anand VC, et al.  (2009) Genome-wide analysis of AP-3-dependent protein transport in yeast. Mol Biol Cell 20(5):1592-604