SUV3/YPL029W Summary Help

Standard Name SUV3 1
Systematic Name YPL029W
Alias LPB2
Feature Type ORF, Verified
Description ATP-dependent RNA helicase; component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron (2, 3)
Name Description SUppressor of Var1 1
Chromosomal Location
ChrXVI:495506 to 497719 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SUV3 GO evidence and references
  View Computational GO annotations for SUV3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
overexpression
Resources
82 total interaction(s) for 74 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 1

Genetic Interactions
  • Dosage Rescue: 10
  • Negative Genetic: 50
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
  • Positive Genetic: 12
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 737
Molecular Weight (Da) 84,324
Isoelectric Point (pI) 9.74
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:495506 to 497719 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2214 495506..497719 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005950
References cited on this page View Complete Literature Guide for SUV3
1) Butow RA, et al.  (1989) The role of a conserved dodecamer sequence in yeast mitochondrial gene expression. Genome 31(2):757-60
2) Dziembowski A, et al.  (2003) The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism. J Biol Chem 278(3):1603-11
3) Turk EM and Caprara MG  (2010) Splicing of Yeast aI5{beta} Group I Intron Requires SUV3 to Recycle MRS1 via Mitochondrial Degradosome-promoted Decay of Excised Intron Ribonucleoprotein (RNP). J Biol Chem 285(12):8585-94