Standard Name	SUV3 1
Systematic Name	YPL029W
Alias	LPB2
Feature Type	ORF, Verified
Description	ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron (2, 3)
Name Description	SUppressor of Var1 1

Chromosomal Location	ChrXVI:495506 to 497719 | ORF Map | GBrowse

	View Computational GO annotations for SUV3
Molecular Function
Manually curated	ATP-dependent RNA helicase activity (IDA) contributes_to exoribonuclease II activity (IDA)
Biological Process
Manually curated	Group I intron splicing (IGI) mitochondrial DNA replication (IMP) mitochondrial RNA catabolic process (IMP)
Cellular Component
Manually curated	colocalizes_with mitochondrial chromosome (IDA) mitochondrial degradosome (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	mitochondrial rho- mutation frequency: increased replicative lifespan: increased respiratory growth: absent
reduction of function	respiratory growth: absent
Large-scale survey
null	cell size: decreased glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased filamentous growth: decreased heat sensitivity: increased invasive growth: absent resistance to doxorubicin: decreased resistance to farnesol: decreased respiratory growth: absent respiratory growth: decreased rate starvation resistance: decreased stress resistance: increased toxin resistance: decreased utilization of carbon source: absent utilization of carbon source: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
overexpression	resistance to LY-83583: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	82 total interaction(s) for 74 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-Western: 1
Genetic Interactions	Dosage Rescue: 10 Negative Genetic: 50 Phenotypic Enhancement: 2 Phenotypic Suppression: 2 Positive Genetic: 13 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:495506 to 497719 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2214 495506..497719 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005950