| Standard Name | SUP61 1 |
|---|---|
| Systematic Name | tS(CGA)C |
| Feature Type | tRNA |
| Description | Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons (2, 3, 4, 5) |
| Name Description | SUPpressor |
| Chromosomal Location | |
|---|---|
| Genetic position: 68 cM |
Gene Ontology Annotations All SUP61 GO evidence and references
| Molecular Function | |
|---|---|
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All SUP61 Phenotype evidence and references
| Classical genetics | |
|---|---|
| gain of function |
interactions All SUP61 Interaction evidence and references
| 2 total interaction(s) for 2 unique genes/features. | |
| Genetic Interactions |
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| Resources |
sequence information
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| Genetic position: 68 cM | |||||||||||||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 2000-05-19 | ||||||||||||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species |
Resources
| External Links | All Associated Seq | Search all NCBI (Entrez) |
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| Primary SGDID | S000006730 |
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References cited on this page View Complete Literature Guide for SUP61
| 1) | Hawthorne DC and Leupold U (1974) Suppressors in yeast. Curr Top Microbiol Immunol 64(0):1-47 |
| 2) | Etcheverry T, et al. (1982) Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. J Mol Biol 158(4):599-618 |
| 3) | Brandriss MC, et al. (1975) Recessive lethal amber suppressors in yeast. Genetics 79(4):551-60 |
| 4) | Lamichhane TN, et al. (2011) Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. RNA 17(10):1846-57 |
| 5) | Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7 |
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