SUP4/tY(GUA)J2 Summary Help

Standard Name SUP4 1
Systematic Name tY(GUA)J2
Feature Type tRNA
Description Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations (1, 2)
Chromosomal Location
ChrX:543044 to 542956 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Genetic position: 36 cM
Gene Ontology Annotations All SUP4 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Large-scale survey
14 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 6

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Suppression: 4
  • Synthetic Rescue: 3

sequence information
ChrX:543044 to 542956 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Genetic position: 36 cM
Last Update Coordinates: 2011-02-03 | Sequence: 2000-05-19
Subfeature details
Most Recent Updates
Coordinates Sequence
Noncoding exon 1..39 543044..543006 2011-02-03 2000-05-19
Intron 40..53 543005..542992 2011-02-03 2000-05-19
Noncoding exon 54..89 542991..542956 2011-02-03 2000-05-19
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000006782
References cited on this page View Complete Literature Guide for SUP4
1) Gilmore RA, et al.  (1971) Amino acid replacements resulting from super-suppression of nonsense mutants of iso-1-cytochrome c from yeast. J Mol Biol 61(1):157-73
2) Chan PP and Lowe TM  (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7