SUI3/YPL237W Summary Help

Standard Name SUI3 1
Systematic Name YPL237W
Feature Type ORF, Verified
Description Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding (2)
Name Description SUppressor of Initiator codon 1
Chromosomal Location
ChrXVI:100496 to 101353 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SUI3 GO evidence and references
  View Computational GO annotations for SUI3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 49 genes
Resources
Classical genetics
conditional
null
Large-scale survey
null
overexpression
Resources
125 total interaction(s) for 51 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 51
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 28
  • Co-fractionation: 1
  • Far Western: 1
  • Reconstituted Complex: 16
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Negative Genetic: 4
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 3
  • Synthetic Rescue: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 285
Molecular Weight (Da) 31,574
Isoelectric Point (pI) 10.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:100496 to 101353 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..858 100496..101353 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006158
References cited on this page View Complete Literature Guide for SUI3
1) Donahue TF, et al.  (1988) Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process. Cell 54(5):621-32
2) Laurino JP, et al.  (1999) The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif. Mol Cell Biol 19(1):173-81