Standard Name	STU2
Systematic Name	YLR045C
Feature Type	ORF, Verified
Description	Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p (1, 2, 3, 4)
Name Description	Suppressor of tub2

Chromosomal Location	ChrXII:237703 to 235037 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for STU2
Molecular Function
Manually curated	microtubule binding (IMP) structural constituent of cytoskeleton (IPI)
Biological Process
Manually curated	microtubule nucleation (IPI) mitotic spindle organization in nucleus (IGI)
Cellular Component
Manually curated	cell cortex (IDA) condensed nuclear chromosome kinetochore (IDA) kinetochore (IDA) spindle microtubule (IDA) spindle pole body (IDA)

Classical genetics
null	inviable
Large-scale survey
conditional	resistance to benomyl: decreased
null	inviable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	160 total interaction(s) for 112 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 1 Affinity Capture-Western: 12 Biochemical Activity: 2 Co-crystal Structure: 2 Co-purification: 1 PCA: 7 Reconstituted Complex: 5 Two-hybrid: 28
Genetic Interactions	Negative Genetic: 76 Phenotypic Enhancement: 4 Phenotypic Suppression: 1 Positive Genetic: 3 Synthetic Growth Defect: 2 Synthetic Lethality: 10 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:237703 to 235037 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2667 237703..235037 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004035