| Standard Name | STU1 |
|---|---|
| Systematic Name | YBL034C |
| Feature Type | ORF, Verified |
| Description | Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles (1, 2) |
| Name Description | Suppressor of TUb2 mutation |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All STU1 GO evidence and references
| View Computational GO annotations for STU1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All STU1 Phenotype evidence and references
| Large-scale survey | |
|---|---|
| conditional | |
| null | |
| overexpression | |
| Resources |
interactions All STU1 Interaction evidence and references
| 187 total interaction(s) for 143 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All STU1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1997-01-28 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000000130 |
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References cited on this page View Complete Literature Guide for STU1
| 1) | Pasqualone D and Huffaker TC (1994) STU1, a suppressor of a beta-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle. J Cell Biol 127(6 Pt 2):1973-84 |
| 2) | Yin H, et al. (2002) Stu1p is physically associated with beta-tubulin and is required for structural integrity of the mitotic spindle. Mol Biol Cell 13(6):1881-92 |




