STE23/YLR389C Summary

STE23 BASIC INFORMATION

Standard Name	STE23
Systematic Name	YLR389C
Feature Type	ORF, Verified
Description	Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family (1, 2)
Name Description	STErile

GO Annotations	All STE23 GO evidence and references
	View Computational GO annotations for STE23
Molecular Function
Manually curated	metallopeptidase activity (ISS, TAS)
Biological Process
Manually curated	peptide pheromone maturation (IGI, IMP) proteolysis (TAS)
Cellular Component
Manually curated	integral to membrane (TAS)

Mutant Phenotype	All STE23 Phenotype details and references
Large-scale survey
null	viable
overexpression	vegetative growth: decreased

Interactions	STE23 All interactions details and references
	7 total interaction(s) for 7 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 1 Two-hybrid: 2

Sequence Information

ChrXII:902660 to 899577 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-05 | Sequence: 2004-02-04

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3084	902660..899577	2004-02-05	2004-02-04

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004381

STE23 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for STE23

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for STE23]

1)	Boyartchuk VL and Rine J (1998) Roles of prenyl protein proteases in maturation of Saccharomyces cerevisiae a-factor. Genetics 150(1):95-101
2)	Adames N, et al. (1995) Role of yeast insulin-degrading enzyme homologs in propheromone processing and bud site selection. Science 270(5235):464-7

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