STE13/YOR219C Summary Help

Standard Name STE13 1
Systematic Name YOR219C
Alias YCI1
Feature Type ORF, Verified
Description Dipeptidyl aminopeptidase; Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor (2, 3, 4)
Name Description STErile
Chromosomal Location
ChrXV:755009 to 752214 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 129 cM
Gene Ontology Annotations All STE13 GO evidence and references
  View Computational GO annotations for STE13
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 931
Molecular Weight (Da) 107,199
Isoelectric Point (pI) 5.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:755009 to 752214 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 129 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2796 755009..752214 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005745
References cited on this page View Complete Literature Guide for STE13
1) Barnes, D. and Thorner, J.  (1985) Personal Communication, Mortimer Map Edition 9
2) Achstetter T  (1989) Regulation of alpha-factor production in Saccharomyces cerevisiae: a-factor pheromone-induced expression of the MF alpha 1 and STE13 genes. Mol Cell Biol 9(10):4507-14
3) Julius D, et al.  (1983) Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell 32(3):839-52
4) Nothwehr SF, et al.  (1993) Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues. J Cell Biol 121(6):1197-209