| Standard Name | STB4 |
|---|---|
| Systematic Name | YMR019W |
| Feature Type | ORF, Verified |
| Description | Putative transcription factor; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters; binds Sin3p in a two-hybrid assay; (1, 2, 3) |
| Name Description | Sin Three Binding protein |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All STB4 GO evidence and references
| View Computational GO annotations for STB4 | |
| Molecular Function | |
| Manually curated | |
| High-throughput | |
| Biological Process | |
| Manually curated |
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| Cellular Component | |
| Manually curated |
Regulatory Role
| Binding motifs | Predicted STB4 Binding Site Locations |
|---|---|
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| Resources |
Mutant phenotypes All STB4 Phenotype evidence and references
interactions All STB4 Interaction evidence and references
| 30 total interaction(s) for 29 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All STB4 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000004621 |
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References cited on this page View Complete Literature Guide for STB4
| 1) | Kasten MM and Stillman DJ (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256(4):376-86 |
| 2) | Ward LD and Bussemaker HJ (2008) Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences. Bioinformatics 24(13):i165-71 |
| 3) | Yang Y, et al. (2010) Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Cell Res 20(11):1276-8 |
| 4) | Harbison CT, et al. (2004) Transcriptional regulatory code of a eukaryotic genome. Nature 431(7004):99-104 |
| 5) | Badis G, et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87 |





