SRP101/YDR292C Summary Help

Standard Name SRP101 1
Systematic Name YDR292C
Feature Type ORF, Verified
Description Signal recognition particle (SRP) receptor alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with the beta subunit, Srp102p (2)
Name Description Signal Recognition Particle 1
Chromosomal Location
ChrIV:1045011 to 1043146 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SRP101 GO evidence and references
  View Computational GO annotations for SRP101
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
null
Large-scale survey
conditional
null
reduction of function
repressible
unspecified
Resources
143 total interaction(s) for 131 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Biochemical Activity: 2
  • Reconstituted Complex: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 82
  • Positive Genetic: 38
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 621
Molecular Weight (Da) 69,278
Isoelectric Point (pI) 7.17
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1045011 to 1043146 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1866 1045011..1043146 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002700
References cited on this page View Complete Literature Guide for SRP101
1) Ogg SC, et al.  (1992) Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae. Mol Biol Cell 3(8):895-911
2) Ogg SC, et al.  (1998) A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit. J Cell Biol 142(2):341-54