SRL4/YPL033C Summary Help

Standard Name SRL4 1
Systematic Name YPL033C
Feature Type ORF, Verified
Description Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p (1, 2, 3)
Name Description Suppressor of Rad53 null Lethality or Suppressor of Rad53 and Lcd1 1
Chromosomal Location
ChrXVI:488207 to 487362 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SRL4 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
6 total interaction(s) for 6 unique genes/features.
Genetic Interactions
  • Negative Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 281
Molecular Weight (Da) 31,925
Isoelectric Point (pI) 7.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:488207 to 487362 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..846 488207..487362 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005954
References cited on this page View Complete Literature Guide for SRL4
1) Choi DH, et al.  (2008) The Mutation of a Novel Saccharomyces cerevisiae SRL4 Gene Rescues the Lethality of rad53 and lcd1 Mutations by Modulating dNTP Levels. J Microbiol 46(1):75-80
2) Perkins EL, et al.  (1999) Yeast and human genes that affect the Escherichia coli SOS response. Proc Natl Acad Sci U S A 96(5):2204-9
3) Lahav R, et al.  (2007) Role of transcription factor Kar4 in regulating downstream events in the Saccharomyces cerevisiae pheromone response pathway. Mol Cell Biol 27(3):818-29