Standard Name	SPS1 1
Systematic Name	YDR523C
Feature Type	ORF, Verified
Description	Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis (2, 3)
Name Description	SPorulation Specific 1

Chromosomal Location	ChrIV:1487038 to 1485566 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SPS1
Molecular Function
Manually curated	protein serine/threonine kinase activity (ISS)
High-throughput	protein kinase activity (IDA)
Biological Process
Manually curated	ascospore formation (IMP) ascospore wall assembly (IMP) protein phosphorylation (ISS)
High-throughput	protein phosphorylation (IDA)
Cellular Component
Manually curated	prospore membrane (IDA)
High-throughput	cytoplasm (IDA) nucleus (IDA)

Regulatory modules	predicted: stressResponse (523)

Classical genetics
null	metal resistance: decreased oxidative stress resistance: increased replicative lifespan: increased resistance to methyl methanesulfonate: increased resistance to tunicamycin: increased
Large-scale survey
null	alkaline pH resistance: decreased competitive fitness: decreased replicative lifespan: increased resistance to gentamycin C1: decreased resistance to mycophenolic acid: decreased resistance to ethanol: decreased resistance to pyrrolidine dithiocarbamate: decreased resistance to 2,4-dichlorophenol: decreased respiratory growth: absent sporulation: decreased starvation resistance: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	100 total interaction(s) for 99 unique genes/features.
Physical Interactions	Affinity Capture-MS: 25 Affinity Capture-RNA: 1 Biochemical Activity: 6 Reconstituted Complex: 22 Two-hybrid: 2
Genetic Interactions	Dosage Growth Defect: 8 Negative Genetic: 31 Phenotypic Suppression: 1 Positive Genetic: 2 Synthetic Growth Defect: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1487038 to 1485566 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1473 1487038..1485566 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002931