SPP41/YDR464W Summary Help

Standard Name SPP41 1
Systematic Name YDR464W
Feature Type ORF, Verified
Description Protein of unknown function; involved in negative regulation of expression of spliceosome components PRP4 and PRP3; relocalizes to the cytosol in response to hypoxia (1, 2)
Name Description Suppressor of PrP4 1
Chromosomal Location
ChrIV:1388872 to 1393179 | ORF Map | GBrowse
Gbrowse
Genetic position: 297 cM
Gene Ontology Annotations All SPP41 GO evidence and references
  View Computational GO annotations for SPP41
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
conditional
null
Large-scale survey
null
overexpression
reduction of function
Resources
15 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Two-hybrid: 2

Genetic Interactions
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,435
Molecular Weight (Da) 161,596
Isoelectric Point (pI) 9.69
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1388872 to 1393179 | ORF Map | GBrowse
This feature contains embedded feature(s): YDR464C-A
SGD ORF map
Genetic position: 297 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4308 1388872..1393179 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002872
References cited on this page View Complete Literature Guide for SPP41
1) Maddock JR, et al.  (1994) Extragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genes. Genetics 136(3):833-47
2) Ghosh Dastidar R, et al.  (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30