Standard Name	SPO22 1
Systematic Name	YIL073C
Alias	ZIP4 2
Feature Type	ORF, Verified
Description	Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis (1, 2)
Name Description	SPOrulation 3

Chromosomal Location	ChrIX:225954 to 222937 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SPO22
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	regulation of synaptonemal complex assembly (IMP)
Cellular Component
Manually curated	colocalizes_with condensed nuclear chromosome (IDA)

Classical genetics
null	meiosis: abnormal meiotic recombination: decreased sporulation: decreased
Large-scale survey
null	acid pH resistance: decreased meiosis: abnormal resistance to 1,4-dithiothreitol: decreased resistance to tunicamycin: decreased spore germination: decreased starvation resistance: decreased toxin resistance: decreased transposable element transposition: decreased vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	9 total interaction(s) for 9 unique genes/features.
Physical Interactions	Affinity Capture-Western: 1 Co-fractionation: 1
Genetic Interactions	Negative Genetic: 5 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:225954 to 222937 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 2003-09-27
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..55 225954..225900 2011-02-03 2003-09-27 Intron 56..145 225899..225810 2011-02-03 2003-09-27 CDS 146..3018 225809..222937 2011-02-03 2003-09-27
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (56 - 145)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001335