SPO21/YOL091W Summary Help

Standard Name SPO21 1
Systematic Name YOL091W
Alias MPC70
Feature Type ORF, Verified
Description Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation; SPO21 has a paralog, YSW1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description SPOrulation 5
Chromosomal Location
ChrXV:145334 to 147163 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SPO21 GO evidence and references
  View Computational GO annotations for SPO21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
75 total interaction(s) for 63 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 6
  • FRET: 4
  • Two-hybrid: 57

Genetic Interactions
  • Dosage Lethality: 1
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 609
Molecular Weight (Da) 69,878
Isoelectric Point (pI) 9.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:145334 to 147163 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1830 145334..147163 2006-01-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005451
References cited on this page View Complete Literature Guide for SPO21
1) Bajgier BK, et al.  (2001) SPO21 is required for meiosis-specific modification of the spindle pole body in yeast. Mol Biol Cell 12(6):1611-21
2) Knop M and Strasser K  (2000) Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis. EMBO J 19(14):3657-67
3) Nickas ME, et al.  (2003) Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Eukaryot Cell 2(3):431-45
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Esposito MS, et al.  (1970) Conditional mutants of meiosis in yeast. J Bacteriol 104(1):202-10