SNT1/YCR033W Summary

SNT1 BASIC INFORMATION

Standard Name	SNT1 1
Systematic Name	YCR033W
Feature Type	ORF, Verified
Description	Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein (1, 2)
Name Description	SaNT domains 1

GO Annotations	All SNT1 GO evidence and references
	View Computational GO annotations for SNT1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	histone deacetylation (IDA) negative regulation of meiosis (IPI) positive regulation of stress-activated MAPK cascade (IMP) regulation of transcription (IMP)
Cellular Component
Manually curated	Set3 complex (IDA)
High-throughput	Rpd3L-Expanded complex (IDA)

Mutant Phenotype	All SNT1 Phenotype details and references
Classical genetics
null	Slt2p modification: decreased histone H3 modification: increased resistance to tunicamycin: decreased resistance to mycophenolic acid: decreased
Large-scale survey
null	competitive fitness: decreased resistance to L-1,4-dithiothreitol: decreased resistance to doxorubicin: decreased viable

Interactions	SNT1 All interactions details and references
	151 total interaction(s) for 99 unique genes/features.
Physical Interactions	Affinity Capture-MS: 37 Affinity Capture-RNA: 1 Affinity Capture-Western: 4 PCA: 1
Genetic Interactions	Phenotypic Enhancement: 55 Phenotypic Suppression: 18 Synthetic Growth Defect: 18 Synthetic Lethality: 16 Synthetic Rescue: 1

Sequence Information

ChrIII:186485 to 190165 | |

Last Update

Coordinates: 2006-01-12 | Sequence: 2000-09-13

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3681	186485..190165	2006-01-12	2000-09-13

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000629

SNT1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SNT1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SNT1]

1)	Pijnappel WW, et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004
2)	Cerna D and Wilson DK (2005) The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex. J Mol Biol 351(4):923-35

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