SNT1/YCR033W Summary Help

Standard Name SNT1 1
Systematic Name YCR033W
Feature Type ORF, Verified
Description Subunit of the Set3C deacetylase complex; interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein; mutant has increased aneuploidy tolerance; relocalizes to the cytosol in response to hypoxia (1, 2, 3, 4)
Name Description SaNT domains 1
Chromosomal Location
ChrIII:186489 to 190169 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SNT1 GO evidence and references
  View Computational GO annotations for SNT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
528 total interaction(s) for 323 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 40
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 4
  • PCA: 1

Genetic Interactions
  • Negative Genetic: 310
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 11
  • Positive Genetic: 115
  • Synthetic Growth Defect: 30
  • Synthetic Lethality: 6
  • Synthetic Rescue: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,226
Molecular Weight (Da) 138,396
Isoelectric Point (pI) 9.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:186489 to 190169 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2000-09-13
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3681 186489..190169 2011-02-03 2000-09-13
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000629
References cited on this page View Complete Literature Guide for SNT1
1) Pijnappel WW, et al.  (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004
2) Cerna D and Wilson DK  (2005) The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex. J Mol Biol 351(4):923-35
3) Torres EM, et al.  (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83
4) Ghosh Dastidar R, et al.  (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30