Standard Name	SNT1 1
Systematic Name	YCR033W
Feature Type	ORF, Verified
Description	Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein; mutant has increased aneuploidy tolerance (1, 2, 3)
Name Description	SaNT domains 1

Chromosomal Location	ChrIII:186489 to 190169 | ORF Map | GBrowse

	View Computational GO annotations for SNT1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	histone deacetylation (IDA) negative regulation of meiosis (IPI) positive regulation of stress-activated MAPK cascade (IMP) regulation of transcription, DNA-dependent (IMP)
Cellular Component
Manually curated	Set3 complex (IDA)
High-throughput	Rpd3L-Expanded complex (IDA)

Classical genetics
null	Slt2p modification: decreased histone H3 modification: increased resistance to tunicamycin: decreased resistance to mycophenolic acid: decreased sporulation: increased rate
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased resistance to caffeine: decreased resistance to camptothecin: decreased resistance to bleomycin: decreased resistance to acetic acid: decreased resistance to tunicamycin: decreased resistance to hydroxyurea: increased resistance to fenpropimorph: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to methyl methanesulfonate: decreased resistance to mycophenolic acid: decreased resistance to sirolimus: decreased resistance to dimethyl sulfoxide: decreased resistance to BPS: decreased resistance to L-1,4-dithiothreitol: decreased resistance to doxorubicin: decreased stress resistance: decreased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	527 total interaction(s) for 325 unique genes/features.
Physical Interactions	Affinity Capture-MS: 40 Affinity Capture-RNA: 2 Affinity Capture-Western: 4 PCA: 1
Genetic Interactions	Negative Genetic: 309 Phenotypic Enhancement: 3 Phenotypic Suppression: 11 Positive Genetic: 115 Synthetic Growth Defect: 30 Synthetic Lethality: 6 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:186489 to 190169 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2000-09-13
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..3681 186489..190169 2011-02-03 2000-09-13
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000629