SNP1/YIL061C Summary Help

SNP1 BASIC INFORMATION

Standard Name SNP1
Systematic Name YIL061C
Feature Type ORF, Verified
Description Component of U1 snRNP required for mRNA splicing via spliceosome; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein (1, 2, 3, 4, 5)
Gene Product Alias U1 70K 3 , U1-70K 1
GO Annotations All SNP1 GO evidence and references
    View Computational GO annotations for SNP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SNP1 Phenotype details and references
Large-scale survey
null
overexpression
Interactions SNP1 All interactions details and references
140 total interaction(s) for 77 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 91
  • Affinity Capture-Western: 13
  • Co-purification: 1
  • Two-hybrid: 34
Genetic Interactions
  • Dosage Rescue: 1
Sequence Information
ChrIX:245556 to 244654 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..903 245556..244654 1994-12-10 1994-12-10
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001323

SNP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SNP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SNP1]

1) Hilleren PJ, et al.  (1995) The amino-terminal domain of yeast U1-70K is necessary and sufficient for function. Mol Cell Biol 15(11):6341-50
2) Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90
3) Smith V and Barrell BG  (1991) Cloning of a yeast U1 snRNP 70K protein homologue: functional conservation of an RNA-binding domain between humans and yeast. EMBO J 10(9):2627-34
4) Kao HY and Siliciano PG  (1992) The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene. Nucleic Acids Res 20(15):4009-13
5) Gunderson SI, et al.  (1998) U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1(2):255-64