SNL1/YIL016W Summary Help

Standard Name SNL1 1
Systematic Name YIL016W
Feature Type ORF, Verified
Description Ribosome-associated protein; proposed to act in protein synthesis and nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein (1, 2, 3)
Name Description Suppressor of Nup116-C Lethal 1
Chromosomal Location
ChrIX:321454 to 321933 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SNL1 GO evidence and references
  View Computational GO annotations for SNL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
Resources
116 total interaction(s) for 108 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 42
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 8
  • Biochemical Activity: 1
  • PCA: 40
  • Reconstituted Complex: 4

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 5
  • Negative Genetic: 8
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 159
Molecular Weight (Da) 18,306
Isoelectric Point (pI) 10.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:321454 to 321933 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..480 321454..321933 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001278
References cited on this page View Complete Literature Guide for SNL1
1) Ho AK, et al.  (1998) The integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function. Mol Biol Cell 9(2):355-73
2) Sondermann H, et al.  (2002) Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae. J Biol Chem 277(36):33220-7
3) Verghese J and Morano KA  (2012) A lysine-rich region within fungal BAG domain-containing proteins mediates a novel association with ribosomes. Eukaryot Cell 11(8):1003-11