| Standard Name | SNG1 1 |
|---|---|
| Systematic Name | YGR197C |
| Feature Type | ORF, Verified |
| Description | Protein involved in resistance to nitrosoguanidine and 6-azauracil; expression is regulated by transcription factors involved in multidrug resistance; SNG1 has a paralog, YJR015W, that arose from the whole genome duplication (2, 3, 4, 5, 6) |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All SNG1 GO evidence and references
| View Computational GO annotations for SNG1 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated | |
| High-throughput |
Mutant phenotypes All SNG1 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| overexpression | |
| Large-scale survey | |
| null |
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| overexpression | |
| Resources |
interactions All SNG1 Interaction evidence and references
| 16 total interaction(s) for 15 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All SNG1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000003429 |
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References cited on this page View Complete Literature Guide for SNG1
| 1) | Haase E, et al. (1992) Isolation and characterization of additional genes influencing resistance to various mutagens in the yeast Saccharomyces cerevisiae. Curr Genet 21(4-5):319-24 |
| 2) | Grey M, et al. (1995) SNG1--a new gene involved in nitrosoguanidine resistance in Saccharomyces cerevisiae. Mutat Res 346(4):207-14 |
| 3) | Le Crom S, et al. (2002) New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol Cell Biol 22(8):2642-9 |
| 4) | Lucau-Danila A, et al. (2003) Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J Biol Chem 278(52):52641-50 |
| 5) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 6) | Garcia-Lopez MC, et al. (2010) Overexpression of SNG1 causes 6-azauracil resistance in Saccharomyces cerevisiae. Curr Genet 56(3):251-63 |





